Pyroluria & Pyrrole Disorder

Pyroluria, also commonly called pyrrole disorder, pyrroles, kryptopyrroles, kryptopyrroluria (KPU), haemopyrrollactamuria (HPL) or Mauve Factor, is a condition that may cause anxiety, poor stress tolerance and outbursts of anger or aggression among a number of other symptoms.

Pyroluria involves an abnormality in haemoglobin synthesis, resulting in the production of excessive amounts of waste products called pyrroles. The general population when tested have less than 10mcg/dL, however pyrrole patients will experience levels above 15-20mcg/dL, including extremely high levels of above 100mcg/dL.

Pyroluria and pyrroles are known to deplete the body of important nutrients, including zinc, vitamin B6, biotin and omega 6 GLA/AA. Zinc and vitamin B6 in particular are essential for daily happiness, stress-coping and a stable mood even when things go wrong.

Common Symptoms

The most common symptoms of pyrrole disorder include:

  • Anxiety, including fear or fearfulness.
  • Poor stress tolerance and difficulty coping with stressful situations.
  • Outbursts of anger, aggression, or an explosive temper.
  • Poor coping with changes in routine, and anxiety in new situations.
  • Sudden changes in mood and emotional lability.
  • Poor short-term memory.
  • Absence of dream recall, not remembering dreams.
  • Sensitivity to light, noise or smells.
  • Poor immune function.

Pyrrole disorder is also often found in children and adults with autism, ADD/ADHD, schizophrenia, Down syndrome, epilepsy, depression, bipolar disorder, criminal behaviour and substance abuse.

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More About Pyroluria & Pyrrole Disorder

Testing for pyrroles

A simple urine test can confirm if you have high pyrrole levels, and with the correct nutritional medicine, dramatic improvements are generally observed within the first few weeks.

Improvements for patients

Correcting elevated pyrrole levels is very rewarding work, with patients usually enjoying resolution of long-standing anxiety disorders and many other mood symptoms, including poor stress tolerance, coping skills and general happiness.

These improvements are usually genuinely life-changing for patients and their families.

Let us guide you to a happier, healthier you.